| Date | Location | Result | |
| May 01, 2022 | Colorado Springs, CO | Colorado College 24, Southwestern (Tex.) 8 | Box score |
| Apr 23, 2022 | River Falls, WI | Colorado College 18, UW-River Falls 13 | Box score |
| Apr 23, 2022 | River Falls, WI | Colorado College 22, UW-La Crosse 1 | Box score |
| Apr 16, 2022 | Atlanta, GA | Oglethorpe 20, Dallas 2 | Box score |
| Apr 16, 2022 | Minneapolis, Minn. | Southwestern (Tex.) 20, Augsburg University 4 | Box score |
| Apr 15, 2022 | River Falls, Wis. | UW-River Falls 19, Southwestern (Tex.) 7 | Box score |
| Apr 14, 2022 | Spartanburg, S.C. | Converse 25, Dallas 4 | Box score |
| Apr 10, 2022 | Galloway, NJ | Stockton Univ. 16, Colorado College 9 | Box score |
| Apr 10, 2022 | Georgetown, Texas | Southwestern (Tex.) 26, Dallas 2 | Box score |
| Apr 09, 2022 | Radnor, PA | Cabrini Univ. 21, Colorado College 12 | Box score |
| Apr 03, 2022 | Claremont, CA | Claremont-M-S 21, Colorado College 12 | Box score |
| Apr 03, 2022 | Conway, Ark. | Hendrix College 23, Dallas 3 | Box score |
| Apr 02, 2022 | Franklin, Ind. | Southwestern (Tex.) 20, Franklin 3 | Box score |
| Apr 01, 2022 | Claremont, CA | Pomona-Pitzer 14, Colorado College 9 | Box score |
| Apr 01, 2022 | Hanover, IN | Southwestern (Tex.) 16, Hanover 5 | Box score |
| Mar 26, 2022 | Georgetown, Texas | Southwestern (Tex.) 21, Whitworth 4 | Box score |
| Mar 25, 2022 | St. Paul, Minn. | Univ. of Chicago 11, Colorado College 4 | Box score |
| Mar 25, 2022 | Irving, TX | Hope 21, Dallas 1 | Box score |
| Mar 24, 2022 | St. Paul. Minn. | Colorado College 22, Hamline Univ. 5 | Box score |
| Mar 24, 2022 | Georgetown, Texas | Southwestern (Tex.) 14, Birmingham Southern 9 | Box score |
| Mar 22, 2022 | Georgetown, Texas | Southwestern (Tex.) 11, Hope 9 | Box score |
| Mar 22, 2022 | Irving, TX | Birmingham Southern 25, Dallas 0 | Box score |
| Mar 21, 2022 | Colorado Springs, CO | Colorado College 23, Hendrix College 4 | Box score |
| Mar 19, 2022 | Colorado Springs, CO | Colorado College 21, McDaniel College 13 | Box score |
| Mar 19, 2022 | Thousand Oaks, CA | Southwestern (Tex.) 18, Pacific (Ore.) 2 | Box score |
| Mar 17, 2022 | Whittier, Calif. | Whittier 18, Southwestern (Tex.) 10 | Box score |
| Mar 16, 2022 | Louisville, Ky. | Hanover 20, Dallas 2 | Box score |
| Mar 16, 2022 | Thousand Oaks, CA | Southwestern (Tex.) 19, Cal Lutheran 4 | Box score |
| Mar 16, 2022 | Colorado Springs, CO | Amherst 12, Colorado College 8 | Box score |
| Mar 14, 2022 | Louisville, Ky. | Dallas 22, Spalding 1 | Box score |
| Mar 12, 2022 | Georgetown, Texas | Southwestern (Tex.) 20, Northwestern-St. Pau 1 | Box score |
| Mar 11, 2022 | Colorado Springs, CO | Colorado College 17, Baldwin Wallace 10 | Box score |
| Mar 09, 2022 | Colorado Springs, CO | Colorado College 15, RIT 8 | Box score |
| Mar 08, 2022 | Georgetown, Texas | Southwestern (Tex.) 15, Ohio Northern 13 | Box score |
| Mar 07, 2022 | Colorado Springs, CO | Colorado College 11, RPI 8 | Box score |
| Mar 06, 2022 | Irving, TX | University of St. Ma 19, Dallas 10 | Box score |
| Mar 05, 2022 | Colorado Springs, CO | Pomona-Pitzer 19, Colorado College 4 | Box score |
| Mar 04, 2022 | Georgetown, Texas | Southwestern (Tex.) 14, Calvin 9 | Box score |
| Mar 01, 2022 | Irving, TX | Calvin 24, Dallas 0 | Box score |
| Feb 26, 2022 | Memphis, TN | Colorado College 21, Ill. Wesleyan 7 | Box score |
| Feb 25, 2022 | Memphis, TN | Rhodes College 11, Colorado College 10 | Box score |
| Feb 18, 2022 | Georgetown, Texas | Southwestern (Tex.) 10, Berry 5 | Box score |